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Today the pronunciation of the Latin 'c' is always like an English 'c' of car for example. In German this is similar to 'k'.
I suppose Acis hasn't been around in common use for long enough to be Anglicised yet, so I'll go along with Akkiss. My initial reaction on seeeing it, though, thanks to our English pronunciation of Acer was to say 'Aessis'. But 'Akkiss' it is.
Actually, I think 'Aessis' sounds nicer than 'Akkiss', and Leucojum runs off the tongue easier than either. I think it'll be a while before I start thinking of them as Acis, I'm sorry to say.
Acis as a genus hasn't been around very long. But in musical circles, the oratorio Acis and Galatea has been known and sung for some time (see previous Wikipedia link) and in those circles (in the UK anyway), it is pronounced Ay-sis. I think Ack-is is probably more "correct" but it's hard to break habits